Main container

Baldini Nicola, MD

Additional Roles


Date of Birth

Full professor at the University of Bologna, Director of Research Unit 

Current assignment

Director of the “Biomedical Sciences and Technologies and Nanobiotechnology” Unit (delib. N.219/2020 del 30/06/2020)

Head of Department Rizzoli RIT- Research, Innovation and Technology (delib. N.312 del 21/10/2020)

Title of qualification awarded

1981: MD Diploma and Licensure, UNIBO

Other qualifications awarded
  • 2018: Management Training Certificate, UNIBO
  • 1990: Specialization in Oncology, UNIBO
  • 1987: Specialization in in Orthopaedic Surgery, UNIBO
Positions held
  • 2020-today: Head of Department Rizzoli RIT- Research, Innovation & Technology
  • 2020-today: Director of  Biomedical Sciences and Technologies & Nanobiotechnology Unit
  • 2018-2020: Head (ad interim)  of Department Rizzoli RIT- Research, Innovation & Technology 
  • 2019-2020: Head (ad interim) of Laboratory of Nanobiotechnology
  • 2017-2020: Head (ad interim) of Laboratory of Musculoskeletal Cell Biology
  • 2011-2020: Head of Orthopaedic Pathophysiology and Regenerative Medicine Unit
  • 2000-2011: Deputy Director, Laboratory of Orthopaedic Pathophysiology and Regenerative Medicine
  • 1999-today: Staff orthopaedic surgeon
  • 1990-1999: Staff scientist, Oncology Research Laboratory
  • 1989-1990: Fellow in Orthopaedic Surgery, Harvard Medical School & Massachusetts General Hospital, Boston, USA
  • 1986: Visiting fellow, Department of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Canada
  • 1987-1989: Research fellow, Cancer Centre, IOR
  • 1982:1987: Fellow, University of Bologna, IOR
  • 1981: Visiting fellow, Department of Surgery, Alder Hey Children’s Hospital, Liverpool, UK
  • English: excellent
Teaching activities
  • 2020-today: Full Professor of Applied Medical Sciences, UNIBO
  • 2019-2023: Member of Collegio Superiore, UNIBO
  • 2016-today: Member of the GTA “Health”, UNIBO
  • 2016-2018: Director of the Training Course in Experimental and Reconstructive Microsurgery, UNIBO
  • 2013-2018: Coordinator of Podiatry Program, UNIBO
  • 2013-2018: Visiting Professor, Kyoto Prefectural University of Medicine
  • 2008-2020: associate Professor of Orthopaedic Surgery, UNIBO
  • 2008-today: Board member of the PhD Program in Biomedical and Neuromotor Sciences, UNIBO
Scientific activities
  • 2021-today: head of the Departmental Centre for Precision Medicine, DIBINEM UNIBO
  • 2020-2023: Scientific Committee member, National Technology Cluster ALISEI- Life Sciences
  • 2019-2020: President, International Society for Cancer Metabolism, ISCaM
  • 2018-today: Co-coordinator of the Research Line “Inflammatory infectious, degenerative and genetic diseases”, IOR
  • 2018-today: Scientific Board member, IOR
  • 2013-2018: Steering Committee member, International Combined Orthopaedic Research Society, ICORS
  • 2009-2012: Steering Committee member, Forum of Italian Researchers on Mesenchymal Stromal Stem Cells, FIRST
  • 2009-2012: Scientific Coordinator, Centre for Biomedical Visualisation, UNIBO
  • 2008-2012: President, European Orthopaedic Research Society, EORS
  • 2009-2012: President, Italian Society for Research in Orthopaedics and Traumatology, IORS
  • 1999-2000: President, Connective Tissue Oncology Society, CTOS (1999-00)

Honorary member of Accademia Gioenia 
Marco Polo Prize for Italian Science (2014)

Participation to research projects in the last 5 years:
  • 2024- today: PI local unit project European Space Agency "Biorider", IOR
  • 2023-today: PI local unit project EC Horizon Europe ORTHO- ALLO- UNION “Orthopaedic treatment with ALLOgenic ATMP combination in UNION and non-UNION long bone fractures”, IOR
  • 2023-today: MUR PRIN 2022 PI local unit project “Targeting the intratumoral microbiota to reverse therapeutic resistance in lethal prostate cancers”, UNIBO
  • 2023-today: PI local unit MINSAL project “Study of GENETIC EVENTS at the baSe of CarcInogeneSi in areas with High Pollution Rates by production type (GENESIS-ATI)”, IOR
  • 2022-today: PI local unit project PNRR CN00000041 RNA “Spoke 2”, National Center for Gene Therapy and Drugs based on RNA Technology, UNIBO
  • 2022-today: PI local unit project PNRR AGE-IT “ “PE08 - AGE-IT A novel public-private alliance to generate socioeconomic, biomedical and technological solutions for an inclusive italian ageing society”, UNIBO
  • 2022-today: PI local unit project PNRR “Sicilian micronanotech research and innovation center- SAMOTHRACE”, IOR
  • 2019-2023: AIRC PI local unit project “Alteration of lipid metabolism as a stress reaction to the acid tumor microenvironment and as a driver of metastasis in osteosarcoma”, UNIBO
  • 2017-2019: Local unit PI, National technology Clusters project “Creation of a multi-regional infrastructure (Italian Regenerative Medicine Infrastructure, IRMI) for the development of advanced therapies for organ and tissue regeneration”, IOR
  • 2018-2021: PI project EC ERANet-LAC “Acid microenvironment as a target for cancer-associated bone pain” IOR
  • 2017-2022: PI local unit project EC-HO2020 “Orthopaedic randomized clinical trial with expanded bone marrow MSC and bioceramics versus autograft in long bone nonunions ORTHOUNION”, IOR

Reviewer: Acta Biomaterials, Acta Orthopaedica, Aging, American Journal of Pathology, Autophagy, Biomaterials, Bioscience, Biotechnology and Biochemistry, BMC Research Notes, British Journal of Cancer, Cancer, Cancer Biomarkers, Cancer Letters, Cancer Management and Research, Cancers, Cell Cycle, Clinical Immunology, European Cell Materials, European Journal of Cancer, , Frontiers in Oncology, Histochemical Journal, International Journal of Cancer, International Journal of Development Neuroscience, Journal of Bone Oncology, Journal of Experimental & Clinical Cancer Research, Journal of Cell Biology and Cell Metabolism, Journal of Clinical Oncology, Journal of Molecular Medicine, Journal of Orthopaedic Translation, Journal of Urology, Medicinal Chemistry Communications, Molecular Oncology, Nature Medicine, Neoplasia, Oncogene, Oncology, Oncotarget, Oncotargets and Therapy, PLOS ONE, Scientific Reports, Stem Cell and Development, Stem Cell International, Stem Cell Reports, The Lancet.

Reviewer of research projects: European Science Foundation, Agence Nationale de la Recerche; National Agency for the Evaluation of the University System and Research; Italian Space Agency; Human Frontier Science Program; Canadian Institute of Health Research; Cancer Society of New Zealand; Centro Investigacion Biomedica en Red Bioingegneria, Biomateriales y Nanomedicina;  Compagnia di San Paolo; Istituto Superiore di Sanità; National Canine Defense League; Societé Française de Lutte Contre les Cancers et Leucémies de l’Enfant et de l’Adolescent; University of Catania. 

Author of more than 300 articles in journals listed in PubMed and Scopus. Total citations: >16,000 (Scopus). H-Index: 66 (Scopus).

Author of 3 books, 31 book chapters, 3 patents, 72 invited seminars and lectures, over 500 congress presentations.

Clinical and/or Scientific interests

Musculoskeletal oncology - Pathophysiology and metabolism of bone – Regenerative medicine – Nanostructured biomaterials - Biointerfaces.

Research Projects

Principal investigator nei seguenti progetti di ricerca.

Research Project
ACIDinCIBP - Acidic microenvironment as a target for cancer-associated bone pain

Acidic microenvironment as a target for cancer-associated bone pain

Read more