Pannella Micaela, MSc, PhD
- 2005: Master degree in Biology, physiology-pathology area at University of Ferrara;
- 2011: PhD degree in Biomedical Sciences/Neurobiology at University of Ferrara;
2006: State exam to register as a qualified biologist, at University of Ferrara
- Present: Research Biologist, Rizzoli Orthopedic Institute, Bologna, Italy;
- 2020-2021: Fellow Research at VIMM (Venetian Institute Molecular Medicine), Padua, Italy;
- 2017-2020: Fellow Research at Fondazione IRET CIRI-SDV, Ozzano nell'Emilia, Bologna, Italy;
- 2014-2016: Fellow Research at Dept. Human Embrionic Stem Cells, Institute of Gene Therapy, School of Medicine Hadassah Ein Kerem, Hebrew University of Jerusalem, Israel;
- 2011-2014: Fellow Research at Cardiology, Biosciences Department, University of Ferrara, Italy;
Excellent knowledge of the Office Suite and of scientific data analysis and calculation (GraphPad Prism, MATLAB). Good proficiency with software for the management and analysis of microscopy images (NIS Elements D, Image J; Software per Life Science Research LAS X Life Science, ZEISS LSM 980 with Airyscan 2).
- Teaching Assistant, University of Ferrara. General Physiology;
- Teaching Assistant, University of Bologna. Translational Medicine;
- Present: A tHeranostic approach to reduce local recurrence of MYxofibrosaRcomA (HYdRA) (Sponsored by Ministry of Health, Italian Government;
- 2020-2021: Biophysical analysis of human midbrain organoids as a model of neuronal dysfunction in Parkinson's disease (Sponsored by PRIN);
- 2017-2020: Improved Functional Recovery in Rat Spinal Cord Injury Induced by a Drug Combination Administered with an Implantable Polymeric Delivery System (Sponsored by POR-FESR);
The pleiotropic molecule NGF regulates in vitro properties of fibroblasts, keratinocytes and endothelial cells: implications for wound healing (Sponsored by Chiesi Farmaceutici);
A dynamic culture platform enhances the efficiency of the 3D HUVEC-based tube formation assay (Sponsored by Fondazione IRET) (Sponsored by Fondazione IRET);
Effects of topic application of CHF6467, a mutated form of human nerve growth factor, on skin wound healing in diabetic mice (Sponsored by Chiesi Farmaceutici);
- 2014-2016: Selection against proliferative progenitors in neuronal cultures for transplantation (Sponsored by BIRAX British Council);
- 2011-2014: Serum from advanced heart failure patients promotes angiogenic sprouting and affects the Notch pathway in human endothelial cell
Main interests: the main interest is aimed at the formation of hybrid organoids that is made up of different cell types such as tumor cells, stromal cells, endothelial cells and components of the extra cellular matrix to understand how they interact with each other and how they modify the surrounding environment.
Maintain these spheroids in microfluidic conditions such as organ on a chip in order to recreate the physiological conditions in which cells live as truthfully as possible.
Another field of considerable interest is understanding how nutrients are able to enter into the tumor mass when it is poorly vascularized and being able to take advantage of this path to introduce drug treatments.