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Manferdini Cristina, MSc


Date of Birth

Laboratory technician

Current assignment

Laboratory technician at the Lab. of Immunorheumatology and tissue regeneration - RAMSES, IOR, Bologna

Title of qualification awarded

2005: Degree in Biomedical laboratory techniques, Faculty of Medicine, University of Bologna.

Positions held
  • 2009 - present  Laboratory technician at the Lab. of Immunorheumatology  and tissue regeneration, IRCCS, IOR, Bologna 
  • August 2014 –November 2014  internships at Tissue Engineering laboratory, Departments of Surgery and Biomedicine, Univerisity Hospital Basel, Switzerland
  • 2006-2008 Research contract at the Lab. of Immunology and Genetics, IOR, Bologna
  • English: level B2, Common European Framework of Reference for Languages
  • French: basic

Excellent skills in the applications of tools for word processing, database management, graphical systems and statistical computing (Microsoft Office, Photoshop, GraphPad,) NIS-Elements image analysis software, Search online bibliographic databases and Internet.

Teaching activities

Tutor for degree theses in Biomedical laboratory’s techniques, Faculty of  Medicine, University of Bologna.

Scientific activities

Participations in research projects:

  • 2019-2023 European project: ADMAIORA Advanced nanocomposite materials for in situ treatment and ultrasound-mediated management of osteoarthritis
  • 2015-2019 European project: ADIPOA2 Adipose derived stromal cells for osteoarthritis treatment. n.643809.
  • 2016-2019 Project funded by Italian Health Ministry " Pain in knee osteoarthritis, a placebo-controlled randomized clinical trial for a new potential therapeutic approach: magnetic resonance guided focusedultrasound surgery (MRgFUS)".
  • 2010-2014 European project: ADIPOA Adipose derived stromal cells for osteoarthritis treatment.
  • 2008-2011 Project funded by Regione Emilia Romagna: Regenerative Medicinee in Osteo-articular diseases
  • 2006-2008 Project funded by Italian Health Ministry: Impiego di cellule staminali adulte (MSC) per terapia tissutale in patologie muscolo scheletriche
  • 2006-2007 European project: STEPS A systems approach to tissue engineering processes and product.
  • Selection at oral presentations in national and international conference.


  • 2019: Best Poster Award for "Specific effects of osteoarthritic milieu and hypoxic conditions on adipose mesenchymal stromal cell migration and cytokine receptor expression" at SCR meeting Napoli, Italy
  • 2017: YOUNG INVESTIGATOR travel grant a ICCBMT (International Conference on the Chemistry and Biology of Mineralized Tissue) Potsdam, Germany
  • 2015: Premio YOUNG Travel bursary 2nd ICRS summit "The Aging Cartilage" (International Cartilage Repair Society) Zermatt (Switzerland) 14-17January 2015

Scientific production:

Publication: 52 in journals with IF (h index=19)


Other activities.

  • Memberships: Osteoarthritis Research  Society International (OARSI), International cartilage repair Society (ICRS), Stem Cell Research Italy (SCR), Gruppo Italiano Staminali Mesenchimali (GISM), Italian Digital Biomanufactoring Network  (IDBN)
  • Reviewer for BioMed Research International, Tissue Engineering, Osteoarthritis Cartilage. Journal of Rheumatic Diseases, Cells, Biology, Pharmaceutics, Biomaterials, IJMS, Scientific reports, Histology and Histophatology,
Clinical and/or Scientific interests

Biomedical research, regenerative medicine and tissue engineering on osteo-articular tissue . In particular, I studied new strategies to promote musculoskeletal tissue healing by stimulating intrinsic properties of MSC , including growth factors and cytokines release, that is a major research issue, recognizing that the regenerative potential of mesenchymal stromal cells is modulated by microenvironment .
 I studied  MSCs behavior in different pathophysiological settings using both static and dynamic  culture conditions, different external stimuli (hypoxia, inflammation,etc.) and different 3D models  (pellet, scaffold, 3D bioprinting).