Main container

Lisignoli Gina, MSc, PhD


Date of Birth

MSc, PhD, Biologist manager

Current assignment

Chief of the "Physiopathology and osteo-articular tissue regeneration" Research Unit (Struttura Semplice) (delibera n.404 del 24/12/2019).

Title of qualification awarded

1986: Degree in Biological Science, with honors, University of Bologna.

Other qualifications awarded

1991: Specialization in Toxicology, with honors, University of Bologna.

Positions held
  • 1986: Degree in Biological Science, cum laude, University of Bologna
  • 1991: Specialization in Toxicology, cum laude, University of Bologna
  • 1989: Scholarship of “Lega Italiana per la lotta contro I Tumori” Institute of Oncology, S.Orsola Hospital,  Bologna, Italy.
  • 1990: Scholarship of U.S.L.28, S.Orsola Hospital,  Bologna, Italy.
  • 1990 – present: Senior Biology Research Manager, Laboratory of Immunorheumatology and Tissue Regeneration, IOR, Bologna, Italy.
  • 2002 – 2009: Assignment of specialist qualification in "Immunology of bone remodeling".
  • 2010 – 2013: High specialty: “Pathophysiology and tissue regeneration”.
  • 2010-2015: Referent of Formation of the Laboratory RAMSES.
  • 2012-2014: Referent of Formation of the Department Rizzoli-RIT.
  • 2006- present: Referent of Formation of the Laboratory of Immunorheumatology and Tissue Regeneration.

English level C1 second Common European Framework of reference for Languages (CEF)


Knowledge and use of Office applications, statistical analysis and Internet.

Teaching activities
  • Tutor for degree thesis in Biological Sciences, Chemistry and Pharmaceutical Technology, Biotechnology and Toxicology, University of Bologna, Italy.
  • Tutor for stage of research in Bio-Sciences, Universitè Paris XII Val de Marne
  • 2012-2015: Contract Professor at School of Pharmacology, Biotechnology and Sports Science, University of Bologna. Course of study: Biology Health.
  • 2014-present Professor at Master of II level at University of Parma: “Cellule staminali ematopoietiche e medicina rigenerativa”.
  • 2020-present Scientific Board member of the PhD Course in “Artificial Intelligence in Medicine and Innovation in Clinical research and Methodology”, at University of Brescia.
Scientific activities

Grants last 10 years:

  • 2008 - 2011 Target research project of Emilia Romagna Region-Bologna University: Regenerative medicine in osteo-articular diseases. Responsible of operative unit.
  • 2010-2014 Project, European Union FP7 “Adipose derived stromal cells for osteoarthritis” (ADIPOA) (n.241719).
  • 2013-2016 Target research project of Emilia Romagna Region-Bologna University: “Regenerative medicine of cartilage and bone”. Responsible of operative unit in WP2.
  • 2015-2019 Project, European Union H2020 “Clinical trial of autologous adipose-derived mesenchymal stromal cells (ASC) in the treatment of mild to moderate osteoarthritis” (ADIPOA2) (n.643809). IOR Responsible of WP4
  • 2017-2019 Project, Ministry of Foreign Affairs, Executive programme for scientific and technological cooperation between the Italian Republic and the Republic of India, “Development of 3D bioprinted Osteochondral tissue” (n.IN17MO03). Italian Responsible.
  • 2019-2023 Project, European Union H2020 “ADvanced nanocomposite MAterIals fOr in situ treatment and ultRAsound-mediated management of Osteoarthritis” (ADMAIORA) (n.814413) . IOR Responsible of WP6.


  • 123 publications in journals with impact factors (3601 citations) h index=34
  • Reviewer of Scientific Journals: reviewer of more than 40 journals
  • Evaluation boards for assignment of research funds: 2002 - present peer-reviewer of Italian MIUR projects (Art. 7; DDL 297/99)
Clinical and/or Scientific interests

Physiopathology of osteo-articular tissue in healthy patients and patients with osteoarthritis, rheumatoid arthritis, osteoporosis: basic research and clinical application. Tissue engineering.


Positioning Device for Ultrasound Probe
Ultrasound probe positioning device suitable for use mainly on a patient’s knee. The Patent has not yet come out of the secrecy period. It is not yet possible to publish more detailed information. For information contact the Technology Transfer Office.  
Read more